Lauren R. Schmitt

Drosophila Arc1 is required for metabolic resilience and developmental timing during dietary challenges

This study shows that Arc1 in Drosophila regulates metabolic resilience and developmental timing in response to dietary changes by linking insulin signaling to metabolic and developmental gene expression.

Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry

The paper develops a method to identify N-terminal cross-linked peptides from collagen I in Achilles tendon using mass spectrometry, revealing differences in cross-links in bovine pulmonary hypertension.

Novel interactions within the silent information regulator heterochromatin complex potentiate inter-subunit communication and gene repression

The paper identifies a novel inter-subunit interaction in the SIR complex that facilitates the switch from histone deacetylation to chromatin compaction, essential for gene repression.

Multi-omics analysis of sarcospan overexpression in mdx skeletal muscle reveals compensatory remodeling of cytoskeleton-matrix interactions that promote mechanotransduction pathways

This study uses multi-omics analysis to show that sarcospan overexpression in mdx mice compensates for dystrophin deficiency by altering cytoskeleton-matrix interactions and mechanotransduction pathways.