Author

Geeta Kumari

Jawaharlal Nehru UniversityORCID 0000-0002-2115-7408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:plant (other)· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Shailja SinghiD· 3 shared Ankita Behl· 2 shared Christoph ArenziD· 2 shared Fernando De LeóniD· 2 shared Monika SainiiD· 2 shared Rumaisha ShoaibiD· 2 shared Aashima GuptaiD· 1 shared Akshay Munjal· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Shailja SinghORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A first-in-Plasmodium study on tRNA intron splicing endonuclease PfTSEN1 and its substrate expression in clinical stage malaria

Mukesh Kumar Maurya, Ankita Behl, Amandeep Kaur Kahlon, Fernando De León, Palak Middha, Reena Nirban, Prerna Joshi, Jhalak Singhal, Geeta Kumari, Akshay Munjal, Rumaisha Shoaib, Neha Jha, Jagriti Pandey, Tanmay Dutta, Christoph Arenz, , Shailja Singh

The paper identifies PfTSEN1 as a tRNA splicing endonuclease in Plasmodium falciparum and demonstrates its inhibition by TSENi, a novel anti-malarial compound.

bioRxiv · Jun 7, 2024 · PreprintMolecular Biology

Human malaria parasite cold shock protein plays an essential role in asexual and sexual stage development and presents an excellent druggable target

Ankita Behl, Monika Saini, Fernando De León, Geeta Kumari, Vikash Kumar, Rumaisha Shoaib, Harshita Singh, Swati Garg, Christoph Arenz, Shailja Singh

This study identifies a cold shock protein in Plasmodium falciparum essential for asexual and sexual stages and shows its potential as a druggable target.

bioRxiv · Jul 7, 2022 · PreprintMolecular Biology

Sphingosine-1-phosphate regulates Plasmodium histone deacetylase activity and exhibits epigenetic control over cell death and differentiation

Raj Kumar Sah, Sakshi Anand, Geeta Kumari, Monika Saini, Rahul Singh Hada, Evanka Madan, Aashima Gupta, Shailja Singh

This study shows that S1P from host erythrocytes regulates PfHDAC-1 activity, affecting transcription of genes related to gametocytogenesis, virulence, and proliferation in Plasmodium falciparum.

bioRxiv · Jun 9, 2022 · PreprintMolecular Biology