Aashima Gupta

This study shows that degrading host p38-MAPK with NR-7h reduces parasite load in Leishmania and Plasmodium infections and enhances antiparasitic therapy when combined with Amphotericin B.

This paper evaluates PF-543, a SphK1 inhibitor, against Leishmania donovani, showing reduced parasite load and enhanced immune response both in vitro and in vivo.

This study identifies mosquito ferritin as a critical iron-storage protein essential for egg development and highlights its potential as a target for malaria control through iron chelation.

This study identifies SphK1 as a druggable target in human macrophages for anti-leishmanial therapy by showing its role in promoting Leishmania donovani survival through immune evasion and cell fate regulation.

The paper assesses the functional relevance of a Plasmodium MFS protein as a drug transporter using Candida glabrata, showing antifungal resistance and antimalarial properties.

This study identifies the Plasmodium prefoldin complex as essential for proteotoxic stress response and demonstrates that biperiden inhibits its function, offering a new drug target for malaria.

This study shows that S1P from host erythrocytes regulates PfHDAC-1 activity, affecting transcription of genes related to gametocytogenesis, virulence, and proliferation in Plasmodium falciparum.