Author

Markus Höpfler

Centre for Genomic RegulationORCID 0000-0002-2129-2220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aseem ShrivastavaiD· 1 shared Axel MogkiD· 1 shared Bernd BukauiD· 1 shared Carmen Ruger-HerrerosiD· 1 shared David S. GrossiD· 1 shared Eva AbsmeieriD· 1 shared Evangelia VartholomaiouiD· 1 shared Fabian den BraveiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Aseem ShrivastavaORCID

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2 papers

Recent·Most cited

Nuclear and cytosolic J-domain proteins provide synergistic control of Hsf1 at distinct phases of the heat shock response

Carmen Ruger-Herreros, Lucia Svoboda, Gurranna Male, Aseem Shrivastava, Markus Höpfler, Katharina Jetzinger, Jiří Koubek, Günter Krämer, Fabian den Brave, Axel Mogk, David S. Gross, Bernd Bukau

This study identifies Apj1 and Ydj1 as J-domain proteins that regulate Hsf1 in distinct phases of the heat shock response in yeast.

eLife · Sep 30, 2025Peer-reviewedMolecular Biology

Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation

Markus Höpfler, Eva Absmeier, Sew‐Yeu Peak‐Chew, Evangelia Vartholomaiou, Lori A. Passmore, Ivana Gasic, Ramanujan S. Hegde

The paper identifies how TTC5 recruits SCAPER to initiate tubulin mRNA degradation via interaction with the CCR4-NOT complex, linking ribosome-associated mRNA decay to microtubule regulation.

Molecular Cell · Jun 8, 2023Peer-reviewedMolecular Biology