Author

Evangelia Vartholomaiou

University of GenevaORCID 0000-0002-8664-9999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ivana GasiciD· 2 shared Markus HöpfleriD· 2 shared Ramanujan S. HegdeiD· 2 shared Alina BatiukiD· 1 shared Ana Coelho AlmeidaiD· 1 shared Deryn En-Jie TeohiD· 1 shared Eva AbsmeieriD· 1 shared Lori A. PassmoreiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Ivana GasicORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay

Alina Batiuk, Markus Höpfler, Ana Coelho Almeida, Deryn En-Jie Teoh, Oscar Vadas, Evangelia Vartholomaiou, Ramanujan S. Hegde, Zhewang Lin, Ivana Gasic

The paper shows soluble β-tubulins sequester TTC5 to regulate tubulin mRNA decay, with loss of sequestration leading to reduced mRNA levels and chromosome segregation defects.

Nature Communications · Nov 17, 2024Peer-reviewedCell Biology

Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation

Markus Höpfler, Eva Absmeier, Sew‐Yeu Peak‐Chew, Evangelia Vartholomaiou, Lori A. Passmore, Ivana Gasic, Ramanujan S. Hegde

The paper identifies how TTC5 recruits SCAPER to initiate tubulin mRNA degradation via interaction with the CCR4-NOT complex, linking ribosome-associated mRNA decay to microtubule regulation.

Molecular Cell · Jun 8, 2023Peer-reviewedMolecular Biology