Molecular insights into dynamic protein structures by high-contrast crosslinking mass spectrometry
Zhuo Angel Chen, Eva Absmeier, James A. W. Stowell, Ludwig Roman Sinn, Shabih Shakeel, Tamara Sijacki, Kendra Njo, Kolja Stahl, Edward Rullmann, Francis J. O’Reilly, Lori A. Passmore, Juri Rappsilber
This paper improves crosslinking mass spectrometry by using diazirine-based photo-crosslinking to better study dynamic protein regions and their conformational changes.
bioRxiv · Sep 2, 2024 · PreprintMolecular Biology