Pat1 globally activates deadenylation-dependent decapping to clear inefficiently translated oligo(A)-tailed transcripts
Lucie Labeauvie, Jackson Peter, Hélène Zuber, Bertrand Séraphin
bioRxiv · Oct 23, 2026 · PreprintMolecular Biology
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Centre National de la Recherche ScientifiqueORCID 0000-0002-2132-4536Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Lucie Labeauvie, Jackson Peter, Hélène Zuber, Bertrand Séraphin
bioRxiv · Oct 23, 2026 · PreprintMolecular Biology
Jackson Peter, Jeanne Roignant, Sebastian Sacharowski, Élodie Ubrig, Benjamin Lefèvre, Szymon Świeżewski, Dominique Gagliardi, Hélène Zuber
This study identifies URT1 as the main enzyme for mRNA uridylation in Arabidopsis, showing its role in shaping the seed transcriptome and regulating primary dormancy.
The Plant Cell · Feb 1, 2026Peer-reviewedPlant Biology
Aude Pouclet, David Pflieger, Rémy Merret, Marie-Christine Carpentier, Marlene Schiaffini, Hélène Zuber, Dominique Gagliardi, Damien Garcia
This study uses multi-transcriptomics to show DNE1 and decapping machinery work together to control mRNA decay and influence siRNA production in Arabidopsis.
bioRxiv · Jan 31, 2024Plant Biology
Hélène Scheer, Caroline De Almeida, Emilie Ferrier, Quentin Simonnot, Laure Poirier, David Pflieger, François M. Sement, Sandrine Koechler, Christina Piermaria, Paweł Szczepan Krawczyk, Seweryn Mroczek, Johana Chicher, Lauriane Kühn, Andrzej Dziembowski, Philippe Hammann, , Dominique Gagliardi
This paper identifies URT1 as a TUTase that connects decapping activators and prevents excessive deadenylation of mRNAs, thereby avoiding siRNA biogenesis in Arabidopsis.
Nature Communications · Feb 26, 2021Peer-reviewedMolecular Biology