Qingquan Zhang

Genomic mosaicism reveals developmental organization of trunk neural crest-derived ganglia

The paper uses genomic mosaicism to study clonal dynamics of trunk neural crest-derived ganglia, finding conserved developmental patterns across species.

MERFISH+, a large-scale, multi-omics spatial technology resolves the molecular holograms of the 3D human developing heart

MERFISH+ enables high-resolution spatial multi-omics mapping of gene expression and chromatin organization in developing human hearts with subcellular resolution.

Single cell multiomics and 3D genome architecture reveal novel pathways of human heart failure

The paper integrates single-cell multi-omics and 3D genome data from human hearts to identify gene regulatory changes and causal genetic contributors in heart failure.

Unveiling unexpected complexity and multipotentiality of early heart fields

The paper reveals unexpected complexity and multipotentiality of early heart fields through lineage and single-cell analyses, identifying new progenitor sources and developmental relationships.

Cardiac Cell Type-Specific Gene Regulatory Programs and Disease Risk Association

The paper defines cardiac cell type-specific cis-regulatory elements and links disease risk variants to these elements in human hearts.