Wei Feng

BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression

This study identifies BST2 as a driver of vascular smooth muscle cell plasticity and macrophage-like phenotype switching in tumors, with implications for immunosuppression and therapy.

The meningeal transcriptional response to traumatic brain injury and aging

This study investigates the meningeal transcriptional response to traumatic brain injury and aging using scRNA-seq and bulk RNA-seq in mice, revealing age-related differences in immune and extracellular matrix gene expression.

Cell-specific chromatin landscape of human coronary artery resolves regulatory mechanisms of disease risk

The paper uses single-cell ATAC-seq to analyze coronary artery cells from CAD patients, identifying regulatory mechanisms and risk variants associated with disease.

Single-cell RNA-seq analysis of human coronary arteries using an enhanced workflow reveals SMC transitions and candidate drug targets

The paper applies an enhanced scRNA-seq workflow to human coronary artery data, revealing SMC transitions and drug targets through ligand-receptor analysis and an interactive web tool.