Author

Chad A. Witt

Washington University in St. LouisORCID 0000-0002-2267-6920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aayusha ThapaiD· 1 shared Andrew E. GelmaniD· 1 shared Catherine CheniD· 1 shared Cory T. BernadtiD· 1 shared Daniel KreiseliD· 1 shared Daniel R. CalabreseiD· 1 shared Dequan ZhouiD· 1 shared Derek E. ByersiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Aayusha ThapaORCID

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1 paper

Recent·Most cited

Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation.

Hrishikesh S. Kulkarni, Laneshia K. Tague, Daniel R. Calabrese, Fuyi Liao, Zhiyi Liu, Lorena Garnica, Nishanth R Shankar, Xiaobo Wu, Devesha Hrishikesh Kulkarni, Aayusha Thapa, Dequan Zhou, Yan Tao, Victoria E. Davis, Cory T. Bernadt, Derek E. Byers, , Andrew E. Gelman

This study identifies a genetic variant linked to impaired complement regulation that worsens chronic lung allograft dysfunction-free survival by promoting B cell activation and donor-specific antibodies.

Journal of Clinical Investigation · Nov 11, 2025Peer-reviewedImmunology