Author

Xiaogang Zhang

University of PennsylvaniaORCID 0000-0002-2280-403XUnclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xiaogang Zhang2 papers · University of Michigan

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander Chan Chi HuangiD· 1 shared Beatriz Goncalves· 1 shared Carl H. JuneiD· 1 shared Fang LiuiD· 1 shared Fei MiaoiD· 1 shared Giorgos Constantine KarakousisiD· 1 shared Haiwei MouiD· 1 shared Huaishan WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander Chan Chi HuangORCID

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1 paper

Recent·Most cited

DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity

Huaishan Wang, Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo, Beatriz Goncalves, Qiuxiang Zheng, Haiwei Mou, Jingbo Yang, Lili Huang, John Scholler, Fei Miao, Tingting Zeng, Giorgos Constantine Karakousis, , Xiaowei Xu

This study develops DR5-targeted CAR-T cells that kill solid tumors and MDSCs, enhance CD8+ T cell activity, and show minimal toxicity in preclinical models.

bioRxiv · Jun 9, 2025 · PreprintCancer Biology