Author

Jingbo Yang

University of PennsylvaniaORCID 0000-0002-6653-2873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Wei GuoiD· 2 shared Alexander Chan Chi HuangiD· 1 shared Beatriz Goncalves· 1 shared Carl H. JuneiD· 1 shared David IssadoreiD· 1 shared Fang LiuiD· 1 shared Fei MiaoiD· 1 shared Giorgos Constantine KarakousisiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

Wei GuoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity

Huaishan Wang, Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo, Beatriz Goncalves, Qiuxiang Zheng, Haiwei Mou, Jingbo Yang, Lili Huang, John Scholler, Fei Miao, Tingting Zeng, Giorgos Constantine Karakousis, , Xiaowei Xu

This study develops DR5-targeted CAR-T cells that kill solid tumors and MDSCs, enhance CD8+ T cell activity, and show minimal toxicity in preclinical models.

bioRxiv · Jun 9, 2025 · PreprintCancer Biology

High-throughput, multiplexed quantification, and sorting of single EVs at single-molecule level

Juhwan Park, Michelle Feng, Jingbo Yang, Hanfei Shen, Zhiyuan Qin, Wei Guo, David Issadore

This paper introduces BDEVS, a platform for high-throughput, multiplexed, and ultra-sensitive profiling of individual extracellular vesicles in plasma, demonstrating a 100x improvement in detecting EV subpopulations.

ACS Nano · May 5, 2025Peer-reviewedBioengineering