Author

Nikhil Janak Pandya

F. Hoffmann-La Roche AGORCID 0000-0002-2286-0576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A FortoniD· 1 shared Adedeji Daniel OgunyemiiD· 1 shared Ahana Dutta· 1 shared Alexis L. RohouiD· 1 shared Andreas F. R. HühmeriD· 1 shared Annamaria Braendli-Baiocco· 1 shared Azad BonniiD· 1 shared Brittany Nortman· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

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2 papers

Recent·Most cited

Large-scale single-molecule analysis of tau proteoforms

James H. Joly, Vivekananda Budamagunta, Zhengjian Zhang, Brittany Nortman, Maryam Jouzi, Rajat Bhatnagar, Jarrett D. Egertson, Michael E. Flaster, Rob Grothe, Sanjib K Guha, Kota Kaneshige, Kevin McVey, Nicholas Nelson, Rukshan T. Perera, Steven J. Tan, , Cara Li

This paper introduces IMaP, a method to analyze tau proteoforms at the single-molecule level, revealing ordered phosphorylation patterns and disease-specific modifications.

Nature Methods · Sep 1, 2026Peer-reviewedBiochemistry

Angelman syndrome patient neuron screen identifies a potent and selective clinical ASO targeting UBE3A-ATS with long lasting effect in cynomolgus monkey

Ravi Jagasia, Charlotte Bon, Soren V. Rasmussen, Solveig Badillo, Disa Tehler, Danièle Buchy, Marco Berrera, Megana K. Prasad, Marco Terrigno, Nikhil Janak Pandya, Veronica Costa, Congwei Wang, Lykke Pedersen, Meghan T. Miller, Kamille Dumong Erichsen, , Marius Christian Hoener

The paper identifies a potent ASO targeting UBE3A-ATS in Angelman syndrome patient neurons, showing long-lasting effects in cynomolgus monkeys.

bioRxiv · Jun 9, 2022 · PreprintNeuroscience