Author

Bridget Shaner

St. Jude Children's Research HospitalORCID 0000-0002-2312-2196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

John B. EastoniD· 2 shared Sivaraman NatarajaniD· 2 shared Andrej GorbatenkoiD· 1 shared Bensheng JuiD· 1 shared Celeste D. RosencranceiD· 1 shared Charles GawadiD· 1 shared Chenxi Qian· 1 shared Daniel K. PutnamiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

John B. EastonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification

Veronica Gonzalez-Pena, Sivaraman Natarajan, Yuntao Xia, David Klein, Robert Carter, Yakun Pang, Bridget Shaner, Kavya Annu, Daniel K. Putnam, Wenan Chen, Jon P. Connelly, Shondra M. Pruett‐Miller, Xiang 'Anthony' Chen, John B. Easton, Charles Gawad

This paper introduces PTA, a new WGA method that improves variant calling accuracy in single cells, enabling studies of genetic diversity and CRISPR off-target effects.

Proceedings of the National Academy of Sciences · Jun 7, 2021Peer-reviewedGenomics

Single-cell analysis identifies TCF4 and ID3 as a molecular switch of mammary epithelial stem cell differentiation.

Koon‐Kiu Yan, Erin A. Nekritz, Bensheng Ju, Xinran Dong, Rachel L. Werner, Dayanira Alsina‐Beauchamp, Celeste D. Rosencrance, Partha Mukhopadhyay, Qingfei Pan, Andrej Gorbatenko, Liang Ding, Yanyan Wang, Chenxi Qian, Hao Shi, Bridget Shaner, , Jiyang Yu

The paper identifies TCF4 and ID3 as key transcription factors driving mammary epithelial stem cell differentiation through single-cell RNA sequencing analysis.

bioRxiv · Aug 16, 2020 · PreprintDevelopmental Biology