Author

Sean A. Pintchovski

ORCID 0000-0002-2345-3884Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alex GriffithsiD· 1 shared Alexis PenverneiD· 1 shared Andrei William Konradi· 1 shared Benjamin J. O’CallaghaniD· 1 shared Darija ŠoltićiD· 1 shared Emily M. RochaiD· 1 shared Eric K. HoffmaniD· 1 shared Hannah J Lucas-ClarkeiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alex GriffithsORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 13, 2025

The SNCA A53T mutation sensitizes human neurons and microglia to ferroptosis

Laura Mahoney‐Sanchez, Hannah J Lucas-Clarke, Alexis Penverne…·Sonia Gandhi

This study shows that the SNCA A53T mutation increases vulnerability to ferroptosis in neurons and microglia, suggesting 15-LO inhibition as a potential therapeutic target for Parkinson's disease.

1 citation

humanproteomics

NeurosciencebioRxivPreprintJun 12, 2024

15-Lipoxygenase-Mediated Lipid Peroxidation Regulates LRRK2 Kinase Activity

Matthew T. Keeney, Eric K. Hoffman, Julie Weir…·J. Timothy Greenamyre

This study identifies 15-lipoxygenase-mediated lipid peroxidation as a regulator of LRRK2 kinase activity, linking it to Parkinson's disease pathogenesis.

3 citations

humanexperimental assay