Author
University of PittsburghORCID 0000-0003-2171-5104Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Caroline Ward, Tabitha Banks‐Tibbs, Henry Thorpe…·Zachary Freyberg
The paper uses AI to analyze pancreatic islet composition in type 1 diabetes, finding age, sex, and region-dependent changes and beta-cell loss with reciprocal cell expansion.
Maria Tsalenchuk, Kyle Farmer, Sandra L. Castro…·Sarah J. Marzi
This study identifies region-specific epigenomic and transcriptomic changes in a rotenone rat model of Parkinson's disease, highlighting immune and synaptic dysregulation in the substantia nigra and cortex.
Matthew T. Keeney, Eric K. Hoffman, Julie Weir…·J. Timothy Greenamyre
This study identifies 15-lipoxygenase-mediated lipid peroxidation as a regulator of LRRK2 kinase activity, linking it to Parkinson's disease pathogenesis.
Silas A. Buck, Sophie A. Rubin, Tenzin Kunkhyen…·Zachary Freyberg
This study identifies VGLUT-mediated mechanisms protecting DA neurons from PD-related degeneration, revealing sex-specific effects and transcriptional regulators.
Briana R. De Miranda, Emily M. Rocha, Sandra L. Castro, J. Timothy Greenamyre
The paper shows that overexpressing TOM20 in rat midbrain neurons prevents α-synuclein-induced dopaminergic neurodegeneration by restoring mitochondrial protein import.