Matthew Neil Rasband

This study identifies Paralemmin 2 as a lipid raft-associated protein that regulates axon initial segments and paranodal junctions through cell type-specific splicing.

This study investigates the roles of PlexinA2, PlexinA4, and NCAM in the development of mossy fibers in the hippocampus, revealing distinct and overlapping functions in axon bundling and targeting.

OASIS enables precise, customizable genome editing and subcellular visualization of adult oligodendrocytes using AAV-mediated CRISPR and biotinylation.

This study investigates the role of oligodendrocyte AnkyrinG in age-related axoglial interactions and behavioral phenotypes, finding that its loss leads to pathophysiological changes in aged mice.

The paper shows TRIM46 is not required for axon specification or AIS formation in mice, contradicting previous cultured neuron studies.

The paper defines the axon initial segment proteome using immunoproximity biotinylation and identifies SCRIB as a highly enriched AIS protein.

The paper identifies Contactin-1 as an AIS cell surface protein that regulates axo-axonic innervation by interacting with Neurofascin and NrCAM.

This study identifies AnkR's role in regulating fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K+ channels in mouse and human.

This study uses in vivo imaging to show that remyelination after oligodendrocyte ablation in mice leads to altered myelin patterns in the cerebral cortex, with impaired regeneration in deeper layers.

This study tests CRISPR/Cas9 with ssODNs and lssODNs for generating conditional knockout alleles in mice, finding higher efficiency with lssODNs.