Author

Timothy Lynch

University College DublinORCID 0000-0002-2380-8737Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Christine KleiniD· 2 shared Owen A. RossiD· 2 shared Aleksander PulykiD· 1 shared Alexander A. ZimprichiD· 1 shared Alexis BriceiD· 1 shared Ali Samii· 1 shared Anat MirelmaniD· 1 shared Anthony Edward LangiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Christine KleinORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinsons disease

Claire Y Chiang, Neringa Pratuseviciute, Yu‐En Lin, Ayan Adhikari, Wondwossen M Yeshaw, Chloe Flitton, Pemba L. Sherpa, Francesca Tonelli, Irena Rektorová, Timothy Lynch, Joanna S. Siuda, Monika Rudzińska, Aleksander Pulyk, Peter Bauer, Christian Beetz, , Suzanne R. Pfeffer

The paper identifies PPM1M as a phosphatase that reverses LRRK2-mediated Rab phosphorylation and links a rare mutation to Parkinson's disease.

Cell Reports · Jul 20, 2025Peer-reviewedCell Biology

Genome-wide association studies of LRRK2 modifiers of Parkinson's disease

Dongbing Lai, Babak Alipanahi, Pierre Fontanillas, Tae-Hwi Linus Schwantes-An, Jan Olav Aasly, Roy N. Alcalay, Gary W. Beecham, Daniela Berg, Susan Bressman, Alexis Brice, Kathrin Brockmann, Lorraine N. Clark, Mark Cookson, Sayantan Das, Vivianna M. Van Deerlin, , Tatiana Foroud

This study identifies genetic modifiers of LRRK2 mutations in Parkinson's disease, finding a significant variant in CORO1C and a polygenic risk score effect on penetrance.

Annals of Neurology · May 3, 2021Peer-reviewedGenetic & Genomic Medicine