Author

Joanna S. Siuda

Medical University of SilesiaORCID 0000-0002-0340-660XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Dennis W. DicksoniD· 2 shared Zbigniew K. WszołekiD· 2 shared Aleksander PulykiD· 1 shared Alexander A. ZimprichiD· 1 shared Ayan AdhikariiD· 1 shared Casey N. CookiD· 1 shared Chloe FlittoniD· 1 shared Christian BeetziD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Dennis W. DicksonORCID

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3 papers

Recent·Most cited

PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinsons disease

Claire Y Chiang, Neringa Pratuseviciute, Yu‐En Lin, Ayan Adhikari, Wondwossen M Yeshaw, Chloe Flitton, Pemba L. Sherpa, Francesca Tonelli, Irena Rektorová, Timothy Lynch, Joanna S. Siuda, Monika Rudzińska, Aleksander Pulyk, Peter Bauer, Christian Beetz, , Suzanne R. Pfeffer

The paper identifies PPM1M as a phosphatase that reverses LRRK2-mediated Rab phosphorylation and links a rare mutation to Parkinson's disease.

Cell Reports · Jul 20, 2025Peer-reviewedCell Biology

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue

Jens O. Watzlawik, Xu Hou, Tyrique Richardson, Szymon L. Lewicki, Joanna S. Siuda, Zbigniew K. Wszołek, Casey N. Cook, Leonard Petrucelli, Michael A. Deture, Dennis W. Dickson, Odetta Antico, Miratul M. K. Muqit, Jordan B. Fishman, Karima Pirani, Ravindran Kumaran, , Wolfdieter Springer

This paper develops and characterizes novel phospho-ubiquitin antibodies to detect low levels of p-S65-Ub, a marker of mitochondrial damage, in cells and tissues.

Autophagy · May 27, 2024Peer-reviewedNeuroscience

Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons

Hu Wang, Rong Chen, Liming Xiao, Manoj Kumar, Jesús A. Acevedo-Cintrón, Joanna S. Siuda, Dariusz Koziorowski, Zbigniew K. Wszołek, Valina Lynn Dawson, Ted M. Dawson

This study shows that defects in mitochondrial biogenesis, not mitophagy, are the primary cause of mitochondrial alterations in PINK1-deficient human dopamine neurons.

bioRxiv · Jun 23, 2023 · PreprintNeuroscience