Pharmacology & ToxicologyBritish Journal of PharmacologyPeer-reviewed
Ethosuximide: subunit- and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channels
Boris Shalomov, Theres Friesacher, Daniel Yakubovich…·Nathan Dascal
This study identifies ethosuximide as a subunit-selective, Gβγ-dependent blocker of GIRK channels, revealing its mechanism of action and potential as a therapeutic tool.
6 citations