Author

Catherine M. Sawai

Université de BordeauxORCID 0000-0002-2509-474XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Audrey Porquet· 1 shared Elina ZuevaiD· 1 shared Emilie Elvira‐MatelotiD· 1 shared Françoise PorteuiD· 1 shared Hassan Ait-Ougouram· 1 shared Jean-Marc Lemaı̂treiD· 1 shared Mathieu BohmiD· 1 shared Mengliang YeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Audrey Porquet

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1 paper

Recent·Most cited

Transient reprogramming limits AP-1-associated chromatin opening and transposable element activation to preserve hematopoietic stem cell function during aging and stress

Audrey Porquet, Mathieu Bohm, Hassan Ait-Ougouram, Thu-Ha Trinh, Rabie Chelbi, Mengliang Ye, Ollivier Milhavet, Jean-Marc Lemaı̂tre, Nathalie M Droin, Elina Zueva, Catherine M. Sawai, Emilie Elvira‐Matelot, Françoise Porteu

This study shows that transient reprogramming with Yamanaka factors delays and partially reverses HSC aging and stress-induced decline by limiting AP-1 chromatin opening and transposable element activation.

bioRxiv · Aug 31, 2026 · PreprintCell Biology