Carla Lopes

The paper shows that oxidative stress causes micronuclear collapse in Parkinson's fibroblasts, leading to DNA export via amphisomes and pro-inflammatory EVs, which can be mitigated by a mitochondria-targeted antioxidant.

This study shows TRIB2 promotes glycolysis in melanoma cells, contributing to therapy resistance and suggesting it as a potential therapeutic target.

The paper shows that extracellular vesicles from healthy cells can reverse GABAergic synaptic deficits in Huntington's disease neurons by modulating miRNA content.

This study investigates mitochondrial dysfunction and redox changes in early Huntington disease stages using human and mouse models, showing increased mitochondrial activity and altered morphology.

This study shows that Huntington's Disease leads to increased release of mitochondrial components via extracellular vesicles due to mitochondrial and lysosomal dysfunction.