Author

Ana Luísa De Sousa‐Coelho

Algarve Biomedical CenterORCID 0000-0002-8451-4302Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana Arrulo Pereira· 1 shared Bibiana I. FerreiraiD· 1 shared Bruno Varzea· 1 shared Carla LopesiD· 1 shared Célia Alexandra AveleiraiD· 1 shared Clévio NóbregaiD· 1 shared David VC Brito· 1 shared José MatosiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Adriana Arrulo Pereira

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Hypothalamic CYP46A1 cholesterol metabolism regulates diet-induced obesity

David VC Brito, Adriana Arrulo Pereira, Renata Sandres de Souza Araujo, Bruno Varzea, Xavier Anastacio, Telma Fontão Castro, Célia Alexandra Aveleira, Sara Carmo‐Silva, Marisa Ferreira‐Marques, Ana Luísa De Sousa‐Coelho, José Matos, Leonor Faleiro, Nathalie Cartier, Sandro Alves, Clévio Nóbrega

This study identifies Cyp46a1 as a critical regulator of diet-induced obesity by modulating body weight, adipocyte size, and metabolic parameters through hypothalamic cholesterol metabolism.

bioRxiv · Jan 12, 2026 · PreprintNeuroscience

TRIB2 supports a high glycolytic phenotype in melanoma cells

Víctor Mayoral-Varo, Ana Luísa De Sousa‐Coelho, Carla Lopes, Óscar H. Martínez-Costa, Paulo Jorge Oliveira, Juan J. Aragón, Bibiana I. Ferreira, Wolfgang Link

This study shows TRIB2 promotes glycolysis in melanoma cells, contributing to therapy resistance and suggesting it as a potential therapeutic target.

bioRxiv · Nov 18, 2025 · PreprintCancer Biology