Yu‐Chieh Chen

A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.

The paper presents a split-GAL4 driver library for targeting neuronal lineages in Drosophila VNC, enabling analysis of morphology, neurochemistry, and behavior.

High-resolution comparative single-cell transcriptomics of doublesex-expressing neurons reveals evolutionary conservation and diversity of sexual circuits in Drosophila

This study uses single-cell transcriptomics to compare doublesex-expressing neurons across Drosophila species, revealing conserved cell types and species-specific gene expression differences in sexual circuits.

Decoding neuronal wiring by joint inference of cell identity and synaptic connectivity

The paper develops ConnectionMiner to integrate scRNAseq and connectome data, revealing gene expression patterns linked to synaptic connectivity in Drosophila leg motor circuits.

Temporal and Notch identity determine neuropil targeting depth and synapse location in the fly visual system

The paper links temporal and Notch identity of medulla neurons to their synaptic location and neuropil targeting depth in the adult Drosophila visual system.

Biased cell adhesion organizes a circuit for visual motion integration

The paper identifies layer-specific receptor-ligand pairs that mediate synaptic specificity in Drosophila visual motion neurons.

Using single-cell RNA sequencing to generate cell-type-specific split-GAL4 reagents throughout development

The paper uses scRNA-seq to generate cell-type-specific split-GAL4 reagents for Drosophila development, demonstrating their effectiveness in targeting known cell types and identifying novel ones.