James William Truman

A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord.

The paper presents a split-GAL4 driver library for targeting neuronal lineages in Drosophila VNC, enabling analysis of morphology, neurochemistry, and behavior.

A split-GAL4 driver line resource for Drosophila neuron types

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

Steering From the Rear: Coordination of Central Pattern Generators Underlying Navigation by Ascending Interneurons

This study investigates how ascending interneurons in Drosophila larvae coordinate motor programs for navigation by modulating central pattern generators.

The embryonic role of juvenile hormone in the firebrat, Thermobia domestica, reveals its function before its involvement in metamorphosis

This study investigates the embryonic role of juvenile hormone in the firebrat, showing its function in suppressing morphogenesis and promoting terminal differentiation before its role in metamorphosis.

Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster

The paper identifies 196 cell types in the Drosophila ventral nerve cord using split-GAL4 and links them to a connectomic dataset for circuit analysis.

Metamorphosis of memory circuits in Drosophila reveal a strategy for evolving a larval brain.

The paper examines the developmental origins and metamorphic fates of neurons in the larval and adult mushroom body circuits of Drosophila to understand how a functional larval brain is formed from a reduced set of neurons.

Circuits for integrating learnt and innate valences in the fly brain

The paper maps convergence neurons in Drosophila that integrate innate and learned olfactory drives to mediate action selection.

Unveiling the sensory and interneuronal pathways of the neuroendocrine connectome in Drosophila

The paper uses electron microscopy to map sensory and interneuronal pathways to neuroendocrine cells in Drosophila, identifying a CO2-responsive network involving Corazonin and Diuretic hormone 44 neurons.

A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS

The paper maps the developmental origin of interneurons in Drosophila and shows how lineage and temporal identity shape synaptic connectivity and circuit formation.

Central processing of leg proprioception in Drosophila

This study identifies three Drosophila neuron types that process leg proprioception, revealing how central circuits integrate sensory information to guide motor behavior.

A Systematic Nomenclature for the Drosophila Ventral Nervous System

The paper provides a systematic nomenclature for the Drosophila ventral nervous system, extending an existing framework to include thoracic and abdominal neuromeres.

Unc-4 acts to promote neuronal identity and development of the take-off circuit in the Drosophila CNS

This study identifies the role of Unc-4 in promoting neuronal identity and development of the take-off circuit in the Drosophila CNS.

Comparative single-cell transcriptomics of complete insect nervous systems

The paper creates a comprehensive atlas of the Drosophila larval nervous system using single-cell transcriptomics and validates findings with RNA-FISH, revealing gene expression changes linked to behavioral states.

Multilevel feedback architecture for adaptive regulation of learning in the insect brain

The paper maps the synaptic connectome of the Drosophila larva mushroom body and identifies feedback pathways that enable modulatory neurons to compute teaching signals for reinforcement learning.

Neural substrates of navigational decision-making in Drosophila larva anemotaxis

This study identifies neuronal circuits in Drosophila larvae that mediate navigational decisions during anemotaxis, showing distinct modules control turning behavior in favorable and unfavorable conditions.

The Feeding Connectome: Convergence of Monosynaptic and Polysynaptic Sensory Paths onto Common Motor Outputs

The paper maps sensory input pathways and their connections to motor outputs in Drosophila larvae, revealing monosynaptic and polysynaptic routes that converge on common motor targets.

Organization Of The Drosophila Larval Visual Circuit

This paper maps the synaptic wiring diagram and neurotransmitters of the Drosophila larval visual circuit, revealing parallel circuits for light intensity and temporal changes.

The Complete Connectome Of A Learning And Memory Center In An Insect Brain

The paper reconstructs the complete synaptic connectome of the Drosophila larval mushroom body, revealing novel circuit structures and input integration patterns in Kenyon cells.