Haluk Lacin

The paper identifies serial homology between neuronal populations in the Drosophila melanogaster brain and ventral nerve cord using lineage reporters, single-cell transcriptomics, and a connectome.

This paper presents a high-resolution developmental transcriptional atlas of the Drosophila nerve cord, identifying three principles governing neuronal diversity and sex-specific differences.

This study shows that loss of dihydroceramide desaturase in glial cells causes neurodegeneration by disrupting ER and lipid droplet homeostasis, leading to neuronal death and developmental defects.

The paper presents a split-GAL4 driver library for targeting neuronal lineages in Drosophila VNC, enabling analysis of morphology, neurochemistry, and behavior.

This study identifies genes regulating CNS morphology in Drosophila through a genetic screen, revealing a role for senseless-2 in surface glia.

The paper uses scRNA-seq to generate cell-type-specific split-GAL4 reagents for Drosophila development, demonstrating their effectiveness in targeting known cell types and identifying novel ones.

This study identifies the role of Unc-4 in promoting neuronal identity and development of the take-off circuit in the Drosophila CNS.

This paper develops a genetically encoded glucose sensor for in vivo imaging across multiple organisms, revealing novel glucose dynamics in neurons, astrocytes, and zebrafish.