Ahmed Negm

This study identifies a previously dormant neuronal circuit in the spinal dorsal horn that becomes active in neuropathic pain, leading to mechanical allodynia.

This study identifies spinal oxytocin circuits as a conserved mechanism through which affiliative touch reduces pain and enhances well-being in mice and humans.

This study investigates mechanical itch hypersensitivity in Shank3 mutant mice, finding somatosensory deficits and two pathways regulating itchiness.

This study shows that high-fat diet-induced obesity in mice increases heat pain hypersensitivity via lysophosphatidylcholine activation of ASIC3 channels in dorsal root ganglia neurons.

This study shows that deleting the TRESK K+ channel enhances mechanical and cold sensitivity in mice, indicating its role in regulating neuronal excitability for specific sensory functions.