Author

Sunnie M. Yoh

Icahn School of Medicine at Mount SinaiORCID 0000-0002-2698-9633Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Sumit K. ChandaiD· 2 shared Adolfo García‐SastreiD· 1 shared Andrew TuckwelliD· 1 shared Asit Kumar MannaiD· 1 shared Ayush Mehta· 1 shared Barbie K. Ganser‐PornillosiD· 1 shared Christian Michel BeuschiD· 1 shared Dale AlleniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Sumit K. ChandaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 31, 2026

PQBP1 couples HIV-1 capsid recognition to cGAS recruitment through conformational remodeling

Dale Allen, Asit Kumar Manna, Christian Michel Beusch…·Sumit K. Chanda

This study shows that HIV-1 capsid binding remodels PQBP1 conformation to enable cGAS recruitment, linking capsid recognition to innate immune activation.

DOI 10.64898/2026.07.07.737097

statistical modelexperimental assay

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Molecular BiologybioRxivPreprintJan 10, 2022

Recognition of HIV-1 capsid licenses innate immune response to viral infection

Sunnie M. Yoh, João I. Mamede, Derrick Lau…·Sumit K. Chanda

The paper identifies a two-factor authentication mechanism used by the innate immune system to detect low-abundance HIV-1 DNA through PQBP1-mediated capsid recognition and cGAS recruitment.

DOI 10.1101/2022.01.10.472699

humanDNA methylation

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