Author

Andrew Tuckwell

UNSW SydneyORCID 0000-0002-8940-7768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Adolfo García‐SastreiD· 1 shared Derrick LauiD· 1 shared Gianguido C. Cianci· 1 shared Heather M. Curry· 1 shared João I. MamedeiD· 1 shared Joshua E. TempleiD· 1 shared Judd F. HultquistiD· 1 shared Lacy M. SimonsiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Adolfo García‐SastreORCID

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1 paper

Recent·Most cited

Recognition of HIV-1 capsid licenses innate immune response to viral infection

Sunnie M. Yoh, João I. Mamede, Derrick Lau, Narae Ahn, María Teresa Sánchez-Aparicio, Joshua E. Temple, Andrew Tuckwell, Nina V. Fuchs, Gianguido C. Cianci, Laura Riva, Heather M. Curry, Xin Yin, Stéphanie Gambut, Lacy M. Simons, Judd F. Hultquist, , Sumit K. Chanda

The paper identifies a two-factor authentication mechanism used by the innate immune system to detect low-abundance HIV-1 DNA through PQBP1-mediated capsid recognition and cGAS recruitment.

bioRxiv · Jan 10, 2022 · PreprintMolecular Biology