Author

James F. Markmann

Harvard UniversityORCID 0000-0002-2762-6535Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

James F. Markmann1 paper · Transplant Surgery, Penn Medicine University of Pennsylvania Philadelphia Pennsylvania USA

Biology Disciplines

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Immunology· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

Alban LongchampiD· 1 shared Alejandro OcampoiD· 1 shared Alex G. CuencaiD· 1 shared Arnaud LyoniD· 1 shared Deling JiaoiD· 1 shared Dharmendra B. Goswami· 1 shared Florent AllagnatiD· 1 shared George McDonald ChurchiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperMolecular Biology

Alban LongchampORCID

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3 papers

Recent·Most cited

Group 2 Innate lymphoid cells promote allograft survival by constraining and inducing anergy in alloreactive CD4+ T cells

Jifu Ge, Weikang Pan, Zijie Xu, Thais Boccia da Costa, James F. Markmann, Ivan Zanoni, Alex G. Cuenca

This study shows that recipient-derived ILC2s promote allograft survival by inducing anergy in alloreactive CD4+ T cells through antigen presentation and the Caspase-3 pathway.

bioRxiv · Jun 3, 2025 · PreprintImmunology

Impaired glycolysis in aged endothelial cells is associated with reduced neovascularisation upon tissue ischemia

Kevin Kiesworo, Thomas Agius, Arnaud Lyon, Michael Robert MacArthur, Jing Zhang, Sébastien Déglise, James F. Markmann, Korkut Uygun, Heidi Yeh, Katrien De Bock, Sarah Jayne Mitchell, Alejandro Ocampo, Florent Allagnat, Alban Longchamp

This study identifies impaired glycolysis in aged endothelial cells as a factor limiting neovascularization during tissue ischemia.

bioRxiv · Jan 26, 2024 · PreprintMolecular Biology

Extensive Mammalian Germline Genome Engineering

Yanan Yue, Weihong Xu, Yinan Kan, Hong‐Ye Zhao, Yixuan Zhou, Xiaobin Song, Jia‐Jia Wu, Juan Xiong, Dharmendra B. Goswami, Meng Yang, Lydia Lamriben, Mengyuan Xu, Qi Zhang, Yu Luo, Jianxiong Guo, , Luhan Yang

The paper modifies pigs' genomes to create organs compatible with human transplantation by inactivating PERVs and engineering immune-related genes.

Nature Biomedical Engineering · Sep 21, 2020Peer-reviewedSynthetic Biology