Aapo Tervonen

The paper uses imaging and modeling to study transient leaks in epithelial tight junctions, finding that dynamic strand breaking and sealing explain leak behavior at the junction level.

This study shows that the nucleus softens during herpesvirus infection due to reduced outward forces and low biomolecular density in the viral replication compartment.

This study shows that substrate viscoelasticity influences how cells sense mechanical deformation through calcium signals, with stiff substrates producing stronger responses and distinct force dynamics.