Soile Nymark

Junction-level imaging and modeling of transient leaks in epithelia predicts a dynamic tight junction strand network

The paper uses imaging and modeling to study transient leaks in epithelial tight junctions, finding that dynamic strand breaking and sealing explain leak behavior at the junction level.

Cone outer segment renewal in vivo involves progressive particle formation at the photoreceptor-RPE interface

This study uses live imaging in zebrafish to show that cone outer segments are removed in small, successive particles at the cone-RPE interface without extracellular accumulation.

Viscoelasticity driven deformation dynamics of the substrate affect mechanically induced Ca2+ signals

This study shows that substrate viscoelasticity influences how cells sense mechanical deformation through calcium signals, with stiff substrates producing stronger responses and distinct force dynamics.

Biomimetic hydrogel platform reveals active force transduction from retinal pigment epithelium to photoreceptors

This study develops a biomimetic hydrogel platform to model RPE-retina interactions, revealing actin-dependent force transduction during photoreceptor phagocytosis.

Circadian Rhythms in Murine Ocular Tissues including Sclera are affected by Neurobasal A Medium Preincubation, Mouse Strain, but not Sex

This study investigates how sex, mouse strain, and culturing conditions affect circadian rhythms in murine ocular tissues, finding that Neurobasal A medium and mouse strain enhance rhythms, while sex does not.

Rhythmicity of photoreceptor outer segment phagocytosis differs between the cone subtypes in the larval zebrafish

The paper shows that phagocytosis of cone outer segments in larval zebrafish varies by cone subtype, with UV and blue cones showing rhythmic peaks while green and red cones are phagocytosed more evenly.

Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina

The paper develops an iterative immunostaining method combined with expansion microscopy and image processing to enhance super-resolution imaging of nuclear lamina structures.