Author
University of TurinORCID 0000-0002-2774-6027Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Noora Pöllänen, Caleb J. Gammon, Fabrizio Pin, Joshua R. Huot, Roberta Sartori, Fabio Penna, Juha J. Hulmi, Andrea Bonetto, Eija Pirinen
This study shows chemotherapy causes NAD+ loss in muscle and liver, with Nrk2 downregulation linked to muscle wasting across multiple models.
bioRxiv · Jul 13, 2026 · PreprintBiochemistry
Lorena Garcia‐Castillo, Giulio Ferrero, Olga Blaževitš, Giulia Francescato, Azra Thaseen Eliass, Natalia E. Cortez, Marc Beltrà, Sonia Tarallo, Barbara Pardini, Paola Costelli, Alessio Naccarati, Valter D. Longo, Fabio Penna
This study shows that fasting-mimicking diets reduce gut microbial dysbiosis in Lynch syndrome mouse models, preserving beneficial bacteria and altering metabolic pathways linked to cancer progression.
Cancer & Metabolism · Jun 30, 2026Peer-reviewedPathology
Marc Beltrà, Noora Pöllänen, Claudia Fornelli, Kialiina Tonttila, Myriam Y. Hsu, Sandra Zampieri, Lucia Moletta, Samantha Corrà, Paolo Ettore Porporato, Riikka Kivelä, Carlo Fiore Viscomi, Marco Sandri, Juha J. Hulmi, Roberta Sartori, Eija Pirinen, Fabio Penna
This study shows that niacin replenishes NAD+ levels, improves mitochondrial function, and reduces cachexia in cancer models and patients.
Nature Communications · Apr 3, 2023Peer-reviewedMolecular Biology
Marc Beltrà, Fabrizio Pin, Domiziana Costamagna, Robin Duelen, Alessandra Renzini, Riccardo Ballarò, Lorena Garcia‐Castillo, Ambra Iannuzzi, Viviana Moresi, Dario Coletti, Maurilio Sampaolesi, Fabio Penna, Paola Costelli
This study shows that PGC-1α in myofibers increases myogenic progenitors and reduces adipogenesis, enhancing muscle regeneration.
iScience · Nov 1, 2022Peer-reviewedMolecular Biology