Author

Abdellatif El Khayari

Université Mohammed VI PolytechniqueORCID 0000-0002-2803-5024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Rachid El FatimyiD· 2 shared Alden John· 1 shared Amelie Kinsey· 1 shared Anna M. KrichevskyiD· 1 shared Christian E. BadriD· 1 shared Evgeny Deforzh· 1 shared Hassan AinaniiD· 1 shared Hayk MnatsakanyaniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Rachid El FatimyORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Integrated single-cell profiling of RNA and DNA interactomes reveals targetable chromatin architectures in cancer

Evgeny Deforzh, Yanhong Zhang, Hayk Mnatsakanyan, Alden John, Amelie Kinsey, Zelong Zheng, Abdellatif El Khayari, Christian E. Badr, Anna M. Krichevsky

The paper introduces SCIENCE-seq, a single-cell interactomics platform that maps RNA-RNA and DNA-DNA interactions in cancer, identifying therapeutic targets through chromatin architectures.

bioRxiv · Aug 17, 2026 · PreprintCancer Biology

m6A modification and prion-like domain proteins converge to dysregulate Neuronal RNA Granules in Alzheimer s disease

Soukayna Boulaassafre, Hassan Ainani, Abdellatif El Khayari, Yuyu Song, Rachid El Fatimy

This study identifies dysregulation of m6A modification and prion-like domain proteins in Neuronal RNA Granules as potential contributors to Alzheimer's disease pathogenesis.

bioRxiv · Jan 20, 2026 · PreprintNeuroscience

Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia

Natania Casden, Vitali Belzer, Abdellatif El Khayari, Rachid El Fatimy, Oded Behar

This study shows that Sema4B on astrocytes enhances microglia reactivity via Plexin-B2, contributing to CNS injury outcomes.

Proceedings of the National Academy of Sciences · May 23, 2024Peer-reviewedNeuroscience