Author

Kexin Xu

Huazhong University of Science and TechnologyORCID 0000-0002-2850-2083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew P. VanDemarkiD· 1 shared Anurag N. ParanjapeiD· 1 shared Barun Kumar MaityiD· 1 shared Caroline Consoli· 1 shared Chengqi XuiD· 1 shared Chris Varghese· 1 shared David M. GauiD· 1 shared David Ryan KoesiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

Andrew P. VanDemarkORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Small molecule intervention of actin-binding protein profilin1 reduces tumor angiogenesis in renal cell carcinoma

David M. Gau, Pooja Chawla, Kexin Xu, Niharika Welling, Jacob Antonello, Caroline Consoli, Monica H. Wei, Sara Zdancewicz, Michael DaSilva, Chris Varghese, Paul G. Francoeur, Haibin Shi, Xucai Chen, Anurag N. Paranjape, Flordeliza S. Villanueva, , Partha Sarathi Roy

This study shows that a small molecule Pfn1 inhibitor reduces tumor angiogenesis in renal cell carcinoma by targeting endothelial cell Pfn1.

Journal of Biological Chemistry · Dec 11, 2025Peer-reviewedCell Biology

Ninjurin2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Vascular Remodeling through Interacting with PDGF Receptor-β

Mengru Jia, Jiahui Zhuo, Xinming Zhao, Ting Liu, Huifang Zhang, Kexin Xu, Pengyun Wang, Chengqi Xu

bioRxiv · May 27, 2025 · PreprintPathology

Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactions

Lizhen Chen, Zhao Zhang, Qinyu Han, Barun Kumar Maity, Leticia Rodrigues, Emily Kate Zboril, Rashmi Adhikari, Su Hyuk Ko, Xin Li, Shawn R. Yoshida, Pengya Xue, Emilie Smith, Kexin Xu, Qianben Wang, Tim H.‐M. Huang, , Zhijie Liu

This study shows that optimal AR NTD multivalent interactions are required for enhancer assembly and transcriptional activity, with excessive condensation impairing function and potentially contributing to disease.

Molecular Cell · Sep 21, 2023Peer-reviewedMolecular Biology