Sara Zdancewicz

This study shows that a small molecule Pfn1 inhibitor reduces tumor angiogenesis in renal cell carcinoma by targeting endothelial cell Pfn1.

This paper introduces DeFrNDs, detergent-free nanodiscs made with engineered membrane scaffold peptides, enabling high-resolution structural analysis of membrane proteins in native lipid environments.

The paper shows that yeast cells lacking Met15 can assimilate inorganic sulfur via Yll058w, but require exogenous methionine or hydrogen sulfide chelators to grow, challenging the traditional view of MET15 as essential for sulfur assimilation.