Weihong Jiang

The paper engineers a probiotic Escherichia coli to degrade nicotine in the gut, reducing NASH in mice by improving liver function and blocking the gut-liver axis.

This study uses CRISPRi screening to identify transcription factors crucial for growth and carbon utilization in Clostridium ljungdahlii, improving ethanol production through deoR optimization.

This study identifies Eggerthella lenta as a key gut bacterium that enhances resveratrol's efficacy through reductive metabolism, producing a more active metabolite.

This paper shows that reducing PLP1 expression in a mouse model of PMD improves myelination, motor function, and lifespan, supporting PLP1 suppression as a therapeutic strategy.