Author

Anne Lynn S. Chang

Stanford MedicineORCID 0000-0002-2869-2147Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Anne Lynn S. Chang1 paper

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ansuman T. SatpathyiD· 2 shared Howard Y. ChangiD· 2 shared Aaron C. Trotman-GrantiD· 1 shared Ana Jimena Pavlovitch-BedzykiD· 1 shared Anthony Francois· 1 shared Arya KhokhariD· 1 shared Asmita BhattacharyaiD· 1 shared Brett N. Olsen· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Ansuman T. SatpathyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Organoid modeling of tumor-associated macrophages reveals phagocytosis checkpoint blockade-induced conversion to an immunosuppressive SPP1+ phenotype

Michitaka Nakano, Lyong Heo, Yu-Ping Yang, Lorena P. Munoz, Yihua Liu, Lei Zhao, Juhyung Park, Eirini Tsekitsidou, Anthony Francois, Jie Liu, Aaron C. Trotman-Grant, Maria Fernanda Henao Echeverri, Cara Coleen Rada, Edward Tran, Arya Khokhar, , Calvin Jay Kuo

The paper uses patient-derived organoids to study TAM responses to CD47 checkpoint blockade, revealing a conversion to an immunosuppressive SPP1+ phenotype in clear cell renal cell carcinoma.

bioRxiv · May 9, 2026 · PreprintCancer Biology

Induced B-Cell Receptor Diversity Predicts PD-1 Blockade Immunotherapy Response.

Yonglu Che, Jinwoo Lee, Farah Abou-Taleb, Kerri E. Rieger, Ansuman T. Satpathy, Anne Lynn S. Chang, Howard Y. Chang

This study identifies induced B-cell receptor diversity as a predictor of PD-1 blockade immunotherapy response across multiple cancer types.

Proceedings of the National Academy of Sciences · May 2, 2025Peer-reviewedCancer Biology

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Ansuman T. Satpathy, Jeffrey M. Granja, Kathryn E. Yost, Yanyan Qi, Francesca Meschi, Geoffrey P. McDermott, Brett N. Olsen, Maxwell R. Mumbach, Sarah E. Pierce, M. Ryan Corces, Preyas Shah, Jason C. Bell, Darisha Jhutty, Corey M. Nemec, Jean Wang, , Howard Y. Chang

The paper uses scATAC-seq to analyze chromatin accessibility in immune cell development and tumor microenvironments, identifying regulatory elements and trajectories associated with cell differentiation and therapy response.

Nature Biotechnology · Aug 1, 2019Peer-reviewedGenomics