Author

Konstantinos Klaourakis

British Heart FoundationORCID 0000-0002-2881-6744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Joaquim Miguel VieiraiD· 3 shared Paul Richard RileyiD· 3 shared David G. JacksoniD· 2 shared Xin Sun· 2 shared Allegra M. Lord· 1 shared Cathy Browne· 1 shared Christophe RavaudiD· 1 shared Cristina Villa del CampoiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersDevelopmental Biology

Joaquim Miguel VieiraORCID

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3 papers

Recent·Most cited

Distinct roles of the Lyve1 lineage in heart development

Konstantinos Klaourakis, Karolina Zvonickova, Jacinta Isabelle Kalisch-Smith, Nicola Smart, Duncan Burnaby Sparrow, David G. Jackson, Paul Richard Riley, Joaquim Miguel Vieira

The paper identifies distinct roles of the Lyve1 lineage in heart development, showing its contribution to multiple cardiovascular cell types and demonstrating functional consequences of genetic perturbations.

bioRxiv · Jan 7, 2026 · PreprintDevelopmental Biology

The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development

Xin Sun, Sophia Malandraki-Miller, Tahnee L. Kennedy, Elad Bassat, Konstantinos Klaourakis, Jia Zhao, Elisabetta Gamen, Joaquim Miguel Vieira, Eldad Tzahor, Paul Richard Riley

This study identifies agrin as a critical regulator of epicardial EMT by localizing dystroglycan to the Golgi apparatus, ensuring ECM-cytoskeletal connectivity and mechanical integrity during heart development.

Development · May 1, 2021Peer-reviewedDevelopmental Biology

Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart

Thomas J. Cahill, Xin Sun, Christophe Ravaud, Cristina Villa del Campo, Konstantinos Klaourakis, Irina-Elena Lupu, Allegra M. Lord, Cathy Browne, Sten Eirik W. Jacobsen, David R. Greaves, David G. Jackson, Sally A. Cowley, William James, Robin P. Choudhury, Joaquim Miguel Vieira, Paul Richard Riley

This study shows that tissue-resident macrophages are essential for lymphatic vessel growth and patterning during heart development by remodeling the vascular plexus.

Development · Jan 18, 2021Peer-reviewedDevelopmental Biology