William James

This study shows human iPSC-derived microglia uptake and process tau fibrils, leading to secretion in extracellular vesicles that can seed tau aggregation in neurons.

This study identifies two potent nanobodies targeting the conserved S2 region of SARS-CoV-2 spike protein that resist viral escape and reduce viral load in a hamster model.

This paper develops a recombinant single-cycle influenza viral vector vaccine against SARS-CoV-2 and SARS-like betacoronaviruses, showing robust immune responses in mice.

This study shows ZIKV alters metabolism in different fetal neuronal progenitors, potentially affecting neurodevelopment during early pregnancy.

This study shows that tissue-resident macrophages are essential for lymphatic vessel growth and patterning during heart development by remodeling the vascular plexus.