Joaquim Miguel Vieira

The paper identifies regulatory elements and transcription factors governing gene expression in the embryonic mesothelium across three organs, revealing conserved and organ-specific mechanisms.

The paper identifies distinct roles of the Lyve1 lineage in heart development, showing its contribution to multiple cardiovascular cell types and demonstrating functional consequences of genetic perturbations.

This study identifies the Slit2-Robo1 pathway as critical for cardiac sympathetic innervation during development, showing reduced innervation in Slit2-/- and Robo1-/- mice.

This study shows SULF1, expressed in the epicardium, regulates HSPG sulfation to control cardiac development by modulating signaling and cell fate.

The paper identifies molecular markers for placental arterial and venous endothelial cells and shows maternal iron deficiency impairs the arterial vascular network.

This study identifies agrin as a critical regulator of epicardial EMT by localizing dystroglycan to the Golgi apparatus, ensuring ECM-cytoskeletal connectivity and mechanical integrity during heart development.

This study shows that tissue-resident macrophages are essential for lymphatic vessel growth and patterning during heart development by remodeling the vascular plexus.