Eleonora Leucci

This study shows that disrupting the amino acid stress response pathway reduces tumor growth in multiple aggressive cancers by targeting chronic metabolic stress adaptation.

This study identifies KDM5B's role in regulating the PRDX/TXN ROS detoxification system in melanoma DTPs, showing that PRDX inhibition increases ROS vulnerability and delays resistance to MAPK inhibition.

This paper introduces Gtag&T-seq, a low-cost single-cell multi-omics method that reveals cell state plasticity and treatment response in melanoma subclones.

The paper identifies ROSALIND as a lncRNA protecting mitochondrial translation from oxidative damage and shows its role in cancer therapy resistance.

This paper identifies a non-enzymatic HDAC inhibitor with anti-tumor and anti-psychedelic effects, showing reduced gene modulation compared to enzymatic inhibitors.