Author

Encar García-Oliver

Centre National de la Recherche ScientifiqueORCID 0000-0002-2936-062XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alja Kozulic-Pirher· 2 shared Édouard BertrandiD· 2 shared Eugenia I. BasyukiD· 2 shared Jean‐Christophe AndrauiD· 2 shared Marie-Cécile RobertiD· 2 shared Ovidiu RadulescuiD· 2 shared Adèle L’Hostis· 1 shared Alexia PigeotiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenomics

Alja Kozulic-Pirher

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2 papers

Recent·Most cited

G-quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausing

Cyril Esnault, Amal Zine El Aabidine, Marie-Cécile Robert, Anne Cucchiarini, Talha Magat, Alexia Pigeot, Soumya Bouchouika, Encar García-Oliver, Kevin Gawron, Eugenia I. Basyuk, Magdalena A. Karpińska, Alja Kozulic-Pirher, Yu Luo, Daniela Verga, Raphaël Mourad, , Jean‐Christophe Andrau

This study identifies G-quadruplexes as promoter elements that exclude nucleosomes and facilitate RNA polymerase II pausing.

Nature Genetics · Jul 22, 2025Peer-reviewedGenomics

Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting

Katjana Tantale, Encar García-Oliver, Marie-Cécile Robert, Adèle L’Hostis, Yueyuxiao Yang, Nikolay Tsanov, Rachel Topno, Thierry Gostan, Alja Kozulic-Pirher, Meenakshi Basu Shrivastava, Kamalika Mukherjee, Věra Slaninová, Jean‐Christophe Andrau, Florian Mueller, Eugenia I. Basyuk, , Édouard Bertrand

The paper uses single molecule imaging to study HIV-1 promoter pausing and finds that stochastic pausing leads to transcriptional bursting in latent cells.

Nature Communications · Jul 23, 2021Peer-reviewedSystems Biology