Matched single-cell chromatin, transcriptome, and surface marker profiling captures in vivo epigenomic reprogramming during basal-to-luminal transition in the mammary gland
Anna A. Karpukhina, Eve Moutaux, Adeline Durand, Alexandra Van Keymeulen, Amélie Viaene, Mélanie Miranda, Louisa Hadj Abed, Simon Besson‐Girard, Marion Lambault, Délia Dupré, Gregoire Jouault, Mélissa Saichi, Juliette Bertorello, Simon Dumas, Mathias Schwartz, , Céline Vallot
The paper introduces OneCell CUT&Tag, a single-cell multi-omics method that captures chromatin, transcriptome, and surface marker data, revealing epigenomic reprogramming during mammary gland basal-to-luminal transition.
bioRxiv · Feb 17, 2026 · PreprintGenomics