Author

Mai Essam Ahmed

Great Ormond Street HospitalORCID 0000-0002-2952-0646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Organism:zebrafish· 1

Frequent Co-Authors

Aditi Aggarwal· 1 shared Afrin Bhattacharya· 1 shared Ai TianiD· 1 shared Guoria Sun· 1 shared Haruka NishimuraiD· 1 shared Ichiro MasaiiD· 1 shared Julien MuffatiD· 1 shared Lu‐Yang WangiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Aditi Aggarwal

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2 papers

Recent·Most cited

ARP2/3 complex mediates the neuropathology of PTEN-deficient human neural cells downstream of mTORC1 and mTORC2 hyperactivation

Navroop K. Dhaliwal, Octavia Yifang Weng, Ai Tian, Aditi Aggarwal, Mai Essam Ahmed, Guoria Sun, Afrin Bhattacharya, Wendy W. Y. Choi, Haruka Nishimura, Pragnya Chakraborty, Xiaoxue Dong, Yuncheng Wu, Michael D. Wilson, Lu‐Yang Wang, Luis F. Parada, , Yun Li

This study identifies the ARP2/3 complex as a downstream effector of mTORC1 and mTORC2 hyperactivation in PTEN-deficient neural cells, showing its inhibition can rescue disease phenotypes.

Proceedings of the National Academy of Sciences · Feb 12, 2026Peer-reviewedNeuroscience

Strip1 regulates retinal ganglion cell survival by suppressing Jun-mediated apoptosis to promote retinal neural circuit formation

Mai Essam Ahmed, Yutaka Kojima, Ichiro Masai

This study shows Strip1 is essential for retinal ganglion cell survival and IPL formation by suppressing Jun-mediated apoptosis in zebrafish.

eLife · Feb 7, 2022Peer-reviewedDevelopmental Biology