Yifang Liu

TF2TG integrates TF-DNA binding, protein-protein interactions, and transcriptomic data to identify and rank potential target genes for Drosophila transcription factors.

This study shows RTF1 is essential for Th17 cell differentiation through H2B monoubiquitination, and its deficiency mimics the effects of RNF40 loss.

This study compares six sequencing-based spatial transcriptomic methods using reference tissues, highlighting molecular diffusion as a key variable affecting resolution and identifying unique attributes of spatial transcriptomic data.

The paper identifies a cholinergic pathway in Drosophila midgut regeneration that triggers Ca2+ waves to heal the epithelium and prevent chronic injury.

The paper shows that tumor-secreted cytokines induce hepatic gluconeogenesis, contributing to hyperglycemia and poor prognosis in cancer cachexia using Drosophila and mouse models.

This paper develops a cell-free method to directly measure infectious viral titer by capturing intact virions with an aptamer and detecting their genomes using FISH.

The paper develops a DNA-enhanced CuAAC ligand for intracellular biomolecule labeling in live cells, demonstrating reduced copper toxicity and effective labeling.

This study develops an optogenetic model of muscle contraction in Drosophila larvae to investigate acute exercise-like responses and identifies transcriptional similarities between fly and human exercise-induced genes.

This paper introduces Haystack, a method to prioritize causal transcription factors from single-cell data, validated in Drosophila, showing high accuracy in identifying drivers of differentiation.

FlyPhoneDB predicts cell-cell communication in Drosophila using scRNA-seq data by calculating interaction scores between ligand-receptor pairs.

The paper characterizes cell types in the fly kidney using snRNA-seq and identifies new clusters, markers, and signaling networks, linking them to mammalian and planarian kidney structures.

DRscDB provides a database for comparing scRNA-seq data across species, enabling searches for orthologous genes and cell type-specific expression patterns.

The paper shows that Drosophila muscle-derived Pvf1 signals to hepatocyte-like cells to suppress lipid synthesis and prevent obesity.

The paper constructs a cell atlas of the adult Drosophila midgut using scRNA-seq, identifying 12 cell types and providing insights into their molecular features and functions.