Author

Callan O’Connor

Tufts UniversityORCID 0000-0002-5699-9955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 5 Approach:statistical model· 5 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Assay:metabolomics· 2 Research Focus:benchmarking· 1 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Gary A. ChurchilliD· 3 shared Gregory R. KeeleiD· 3 shared Laura G. ReinholdtiD· 3 shared Whitney Martin· 3 shared Angelo D’AlessandroiD· 2 shared Anne CzechanskiiD· 2 shared Ariel M. HayiD· 2 shared Daniel StephensoniD· 2 shared

Activity by Year

2023-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersGenomics

Gary A. ChurchillORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The Flame Retardant Triphenyl Phosphate Induces Varying Responses in Genetically Diverse Mouse Induced Pluripotent Stem Cells

Madison Armstrong, Kathryn Janeczko, Hannah B. Dewey, Anne Czechanski, Qiongyu Chen, Emily Swanzey, Callan O’Connor, Whitney Martin, Selcan C. Aydin, Steven C. Munger, Laura G. Reinholdt

The study examines how genetic variation in mouse induced pluripotent stem cells affects gene expression and cell cycle responses to triphenyl phosphate exposure.

bioRxiv · Sep 28, 2026 · PreprintGenomics

Genetic architecture of the murine serum metabolome reveals carboxyl esterases as master regulators of circulating fatty acid metabolism

Gregory R. Keele, Travis G. Nemkov, Ariel M. Hay, Matthew J. Vincent, Callan O’Connor, Daniel Stephenson, Grier P. Page, James C. Zimring, Gary A. Churchill, Angelo D’Alessandro

The paper identifies genetic regulators of the murine serum metabolome, highlighting carboxyl esterases as key controllers of fatty acid metabolism.

bioRxiv · Jun 28, 2026 · PreprintGenomics

Molecular and genetic heterogeneity in iPSCs derived from an outbred laboratory mouse population

Madison Armstrong, Anne Czechanski, Emily Swanzey, Qiongyu Chen, Whitney Martin, Callan O’Connor, Catherine Brunton, Selcan C. Aydin, Hannah B. Dewey, Steven C. Munger, Laura G. Reinholdt

The paper generates a genetically diverse panel of iPSCs from a mouse population and identifies regulatory loci influencing gene expression variation.

bioRxiv · May 3, 2026 · PreprintGenetics

Genetic architecture of the red blood cell proteome in genetically diverse mice reveals central role of hemoglobin beta cysteine redox status in maintaining circulating glutathione pools

Gregory R. Keele, Monika Dzieciątkowska, Ariel M. Hay, Matthew J. Vincent, Callan O’Connor, Daniel Stephenson, Julie A. Reisz, Travis G. Nemkov, Kirk Charles Hansen, Grier P. Page, James C. Zimring, Gary A. Churchill, Angelo D’Alessandro

The paper identifies genetic factors influencing red blood cell proteome and oxidative stress in mice, highlighting hemoglobin cysteine redox status as critical for glutathione regulation.

bioRxiv · Feb 27, 2025 · PreprintGenomics

Cell morphology QTL reveal gene by environment interactions in a genetically diverse cell population

Callan O’Connor, Gregory R. Keele, Whitney Martin, Timothy J. Stodola, Daniel M. Gatti, Brian R. Hoffman, Ron Korstanje, Gary A. Churchill, Laura G. Reinholdt

The paper identifies cell morphology quantitative trait loci (cmQTL) in fibroblasts exposed to arsenic, revealing gene-environment interactions and genetic regulation of oxidative stress responses.

bioRxiv · Nov 18, 2023 · PreprintGenetics