Cell BiologyBiochemical JournalPeer-reviewed
Substrate-specific regulation of the mTORC1 pathway by G protein-coupled receptors
Samuel J. Atkinson, Florentina Negoita, Yuichiro Ioi…·Riko Hatakeyama
This study shows that GPCRs regulate mTORC1 substrates differently, with M5R promoting protein synthesis while allowing lysosome biogenesis.
DOI 10.1042/bcj20260165