Renata Santos

A Role for Astrocyte Metabolism in Species-Specific Neuronal Development

This study shows that human astrocytes have distinct metabolic profiles compared to non-human primate astrocytes, which influence neuronal development timing and trajectories.

Human AUTS2 regulates neurodevelopmental pathways via dual DNA/RNA binding.

This study identifies AUTS2's dual DNA/RNA binding in human neural progenitors and shows its role in regulating Wnt pathway genes, linking its disruption to neurodevelopmental disorders.

Sex-dependent effects of a gestational ketogenic diet on offspring birth and lifespan

This study examines the effects of a gestational ketogenic diet on mouse offspring, finding reduced litter size, altered sex ratios, and sex-dependent impacts on lifespan and body mass.

Opioid-Induced Inter-regional Dysconnectivity Correlates with Analgesia in Awake Mouse Brains

This study examines opioid-induced changes in brain activation and functional connectivity in awake mice, finding that dysconnectivity correlates with analgesia.

Network size affects the complexity of activity in human iPSC-derived neuronal populations

The paper investigates how network size affects neural activity dynamics in human iPSC-derived neuronal cultures, finding that varying neuron densities alters both individual cell properties and collective network behavior.