Author

Rick Li

Broad InstituteORCID 0000-0002-3098-0885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adam S. ButterworthiD· 1 shared Adriana MendeziD· 1 shared Aitzkoa Lopez de Lapuente PortillaiD· 1 shared Allison E. Ashley‐KochiD· 1 shared Andrew LeeiD· 1 shared Angelika Hammerer‐LercheriD· 1 shared Anna Bárbara Carneiro-Proietti· 1 shared Baraka Stewart MkumbeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adam S. ButterworthORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Human genetics implicates a BACH2-NRF2 axis in fetal hemoglobin activation

C. Guo, Uma P. Arora, Xiaoheng Cheng, Wanying Xu, Liam D. Cato, Rick Li, Henry Y. Lu, Andrew Lee, Fulong Yu, Gaurav Agarwal, Peng Lyu, Tianyi Ye, Mateusz Antoszewski, Mariel Wissmann, Baraka Stewart Mkumbe, , Vijay G. Sankaran

This study identifies a BACH2-NRF2 axis regulating fetal hemoglobin activation through genetic and functional analyses in a large multi-ancestry cohort.

Nature · Sep 30, 2026Peer-reviewedGenetic & Genomic Medicine

Orthoflaviviruses use diverse binding modes to engage LDLR family receptors

Chenggong Ji, Laurentia V. Tjang, Biswajit Das, Qiu Yu J. Huang, Rick Li, Cecilia A. Bradley, Jessica Oros, Side Hu, Wanyu Li, Xiaoyi Fan, Zhiqi Liu, Jonathan Abraham

This study determines cryo-EM structures of orthoflaviviruses bound to LDLR family receptors, revealing distinct binding modes and receptor engagement mechanisms.

bioRxiv · Aug 24, 2026 · PreprintMicrobiology